The Super NES was released in North America on Augwith its launch titles being Super Mario World, F-Zero, Pilotwings, Gradius III and SimCity (Super NES).

There are 970 Japanese exclusives, 121 US exclusives, and 34 European exclusives.

293 releases are common to all regions, 148 were released in Japan and the US only, 163 in Europe and the US, and 30 in Japan and Europe. Of the console's 1758 official releases, 721 were released in North America, 517 in Europe, 1,448 in Japan, 231 on Satellaview, and 13 on Sufami Turbo. Alternatively, disconnecting one pin of the console's lockout chip will prevent it from locking the console, although hardware in later games can detect this situation. This can be overcome through the use of adapters, typically by inserting the imported cartridge in one slot and a cartridge with the correct region chip in a second slot. Internally, a regional lockout chip within the console and in each cartridge prevents PAL region games from being played on Japanese or North American consoles and vice versa.

The physical incompatibility can be overcome with use of various adapters, or through modification of the console. The cartridges are shaped differently for different regions North American cartridges have a rectangular bottom with inset grooves matching protruding tabs in the console, while other regions' cartridges are narrower with a smooth curve on the front and no grooves. The Super Nintendo Entertainment System video game console has a library of games, which were released in plastic ROM cartridges.

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